Wolves have a long running history with mankind, and have since ancient times been feared for preying on livestock. Although it were far from common for wolves to attack human beings before the Great War - much due to mankind's hatred of wolves - the long lack of exposure to humans the post-apocalyptic world heralded has enabled them to move past their instinctive fear of human beings.
Wolves are quadrupedal canines, much like dogs, and travel in large packs. They are substantially larger and stronger than the common dog, and are visually very similar to breeds such as German shepherds or many sled dogs. Individually they pose no major threat to experienced players, but due to their tendency to travel in large packs with their kin they can be quite dangerous.
Wolves are one of the very few creatures to have been left largely unaffected by radiation since the War. Although they were dying out in North America before the War, the commonplace encounters with them during the 22nd and 23rd century indicates that their species has had plenty of time to repopulate; this quite successfully.
Wolfs are encountered in packs of 3 or 4 members. In early stages of the game they can mean trouble for low level players. With the help of they high agility and running patters, they can easily overhelm the player and cause him/her to miss often.