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William may refer to:
- William, an initiate in the Followers of the Apocalypse in Fallout.
- William Brandice, an Enclave deserter found dead in Marigold station in Fallout 3.
- William Farber, an NCR cook stationed at Camp McCarran in Fallout: New Vegas.
- William Mayson, a maintenance worker of Vault 3 before the Fiend invasion in Fallout: New Vegas.
- William Ennis, an employee at the Sierra Madre, mentioned in the Fallout: New Vegas add-on Dead Money.
- William Shippard, a man who lived before the American Revolutionary War, mentioned in Fallout 4.
- Dr. William Moseley, a special-purpose Institute field operative in the Fallout 4 add-on Far Harbor.
- William Black, the second-in-command for the Operators in the Fallout 4 add-on Nuka-World.
- William Lee, the founder of the coffee brand Packed Full Of Joe before the Great War, mentioned in the Fallout 4 add-on Nuka-World.
- Real-life people:
- William H. Keith, Jr., one of the authors of the Fallout Official Survival Guide..
- William Saunders, a developer who worked at Interplay Entertainment as a quality assurance tester for Fallout 2.
- William Killeen, a developer who worked at Bethesda Softworks as an additional quest designer and additional writer for Fallout 3.
- William Bassett, a voice actor who voiced Owyn Lyons in Fallout 3.
- William Sadler, an actor who voiced Victor in Fallout: New Vegas.
- William Mapother, an American actor who voiced James Hsu in Fallout: New Vegas.
- William Shen, a developer who worked at Bethesda Softworks on Fallout 4 as a quest designer and writer.