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Wilkins may refer to:
- Janice Wilkins, a resident of Vault 101, found dead in Fallout 3.
- Jim Wilkins, the brother of Janice Wilkins and resident of Vault 101, found dead in Fallout 3.
- Officer Wilkins, father of Janice and Jim Wilkins and a member of Vault 101 security in Fallout 3.
- Jenny Wilkins, a mother that had not paid her parking tickets, mentioned in Fallout 3.
- Jas Wilkins, a relative of Rose who runs the mess hall in Sloan in Fallout: New Vegas.