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|Miscellaneous quest: Virgil's Cure|
|Quest starts automatically when speaking with Virgil during the main story quest the Glowing Sea.|
|Travel to The Institute.|
|Find and enter the FEV lab.|
|Find and take the serum.|
|Return to Virgil at the Rocky Cave.|
|Give Virgil the cure.||Tell Virgil you'll stop looking for the cure.||Convince Virgil there is no cure.|
|Return to see Virgil 3 days later.||Fight against Virgil.||Accept to end Virgil's life.|
|Rewards: Virgil returns to human form.|
The Rocky cave is freely usable and lootable.
|Reward: Virgil's rifle|
Virgil's Cure automatically starts when talking to Brian Virgil in the main story quest "The Glowing Sea." In the conversation the Sole Survivor first has with Virgil, he requests serum in exchange for his information about the Institute. From this point, the quest cannot be advanced until the player character makes their way to the Institute later in the game.
When in the Institute, find the FEV lab, an old locked area of the Bioscience lab. There's a back entrance with a Master terminal in the main room of the Bioscience lab. This leads directly to the room the serum is in, and also the main entrance to the FEV lab, found at the end of some seemingly abandoned storage halls and rooms. Once in the FEV lab, travel through it to the end room, where the serum is located. The lab will be defended by several turrets and also an assaultron but is otherwise uninhabited. The serum is in the final room in a lab machine on top of a desk.
Bring the serum back to Virgil. The player character has two options:
- One can simply give Virgil the serum, and certain companions will react differently to this choice. For example, John Hancock, Piper, Nick Valentine, Codsworth and Curie like the player character's choice to cure Virgil, but Danse won't like it at all; this is due to what happened with his friend Cutler. Strong also won't like it as he prefers being a super mutant and is angry with the doctor's ambitions to cure the others.
- One can also lie to Virgil through a sequence of three speech checks, claiming that the serum wasn't there. Check difficulty increases with each one. After the first two checks the player character still has the option to give the serum to Virgil through breaking and re-initiating dialog with him. After the third speech check Virgil requests that the player character kill him and the quest will fail. If the player character has visited Swan's Pond and read the notes there, they can ask Virgil if he remembers Edgar Swan after the first speech check. This will lead to a medium speech check to convince him to end his life (bypassing the hard check).
After giving the serum to Virgil, wait three days and return to find he has transformed back into a human. Speak with him again and he'll offer the player character his lab for use, which will make all items therein available for looting.
- This quest never shows as itself under Miscellaneous quests; only two of its last stages come with their own names.
- The quest requires Novice lockpicking and hacking skills only to get through the doors within the FEV lab, which itself is locked (Master) within the Bioscience dome of the Institute.
- The turrets and assaultron in the lab are deadly to those without good energy resistance.
- pc ps4 xboxone Virgil may become hostile while you are wearing a X-01 power armor suit or a power armor helmet with the targeting mod installed.[verified]
- ps4 xboxone This miscellaneous quest may not be given but if you return the cure without having the quest anyway, it may continue even though a marker was not given. [verified]
- pc Using the console to duplicate the experimental serum before completing the quest, will result in it being uncompletable. As the option to give the serum to Virgil will have its text removed. Clicking that option anyway will result in either nothing happening or activate the cutscenes with no dialogue.[verified]
- When getting into the FEV lab through the novice locked door there may be another door that cannot be interacted with and will bar passage into the FEV lab. This is caused by the Unofficial Fallout 4 patch. If you save and exit to menu in that room with the uninteractable door and disable the Fallout 4 Unofficial patch then load back in the door will still be closed and you need to leave the room then reenter and it will be unblocked.[verification needed][platforms tag needed]