Before the Great War, the building was the headquarters for the Sierra Madre Casino's police and security personnel. The terminal entries on the police chief's personal terminal prove that corruption was present among either all or part of the casino's security detail.
The station contains all that a once-bustling police station in a high end area would need: several cells for individual prisoners and a larger cell for people who have committed less dangerous infractions. The larger cell contains Dog. The police station may also be one of the more difficult locations to traverse, as several radios can be found throughout the police station, and even several will be found in one room. The police station does boast some amenities, such as a usable bed and a reloading bench that can be found in the third room to the right of Dog's cage.
The contraband room is located immediately left of the main entrance to the police station, but to access the room, the Police Chief's terminal (hard difficulty) must be hacked. Reading the "Prohibited Items" entry on the terminal will count towards the History's Sake challenge. Inside the contraband room are various weapons, ammunition and other miscellaneous items.
The basement consists of five rooms. There are various containers and lockers with random miscellaneous loot in each, including Sierra Madre chips. The first room has a terminal with some background information and a step ladder that leads to ammunition and Fixer on top of the tall wooden boxes. A janitor's closet, to the right upon entering the second room, has some liquor and a bottle of Buffout in open containers, and a copy of Grognak the Barbarian lying on the floor. The final room contains the Dog command tape.
- Dog command tape - in the basement of the station, is used to free Dog and God from his cell, and to turn Dog into God.
- Vending machine code - "Steady" on a table in a nook to the right of the entrance with several coffee cups on it.
- Vending machine code - "Weapon repair kit" on top of a filing cabinet at the far end of the hall with the prison cells.
- Vending machine code - ".308 rifle rounds" in the far left bathroom.
- Vending machine code - ".357 magnum rounds" in the contraband room, the contraband room is the one unlocked by the Chief's terminal (Science 75).
If Dean Domino is a companion, when nearing the police station, he is reluctant to get any closer for fear of the ghost people there, stating that the ghost people use the area to hunt in. However, in reality, there is only a single one outside the station and none inside.