The Vault-Tec medical protocol is a type of reference source. Written before the Great War of 2077, these protocols are intended as a valuable tool to help vault physicians with the various assortment of ailments they may face in a Vault population. The protocols are the notes of physicians who lived in prototype Vaults recorded and codified for later use.
In the early 2270's, Vault 101's vault physician, James, consulted the Vault-Tec medical protocols for information on Vault depressive syndrome, or VDS, when diagnosing Freddie Gomez. The protocols recommended Chlorpromazine, an anti-anxiety medication, for VDS.