Vance is the 41 year old leader of The Family. When he was younger, he decided that life in Rivet City wasn't for him and began to wander the wasteland. Soon, the ability to find others of his kind manifested itself. Over time, he gathered these outcasts and founded their home in Meresti. Using his traits as a basis and wanting to establish some sort of society, he molded the residents into "vampires" and taught them their bloodsucking ways.
He is a fair leader and has never demanded anyone do anything they didn't wish to do, nor does he wish to put anyone in harm's way. He sees himself as a leader, but more in the way of a guide or a priest than a king. He addresses the residents of Meresti often so they will never "stray from their true nature" - that of the vampire. Vance is not violent and only attacks or orders attacks when survival demands it.
Vance has a very high amount of hit points, being significantly tougher than a standard human non-player character. His durability is slightly less than that of a joinable non-player character companion and (with his armor), slightly more than that of a super mutant brute. His weapon of choice is the Shishkebab. Combat with him can be difficult, if the player character chooses to deal with the Family violently.
Blood Ties: Lucy West in Megaton hasn't heard from her brother Ian West in a while and asks you to go to his home in Arefu to investigate. When you arrive, you discover Ian missing and their parents savagely murdered in their home. Evan King, the de facto leader of the small town, also asks you to find out what's happened to Ian. Unbeknownst to everyone, he has been adopted into the Family by its leader, Vance. To discover Ian, Vance, the Family and the rest of their story, travel to their underground headquarters located in the Meresti trainyard.
If you convince him to accept blood packs from Arefu you can then give him any blood packs you have for caps.
To gain positive Karma and friendship with the Family, you can make a deal with Vance. You can have the citizens of Arefu donate the Family a periodic supply of blood packs to keep them sustained and to ensure they no longer harass the town.
Upon completing Blood Ties, Vance awards the player his copy of the Shishkebab schematics, no matter what dialogue options were chosen.
Vance is the only source of the Hematophage perk which causes blood pack to yield 20 HP each rather than the normal 1 HP. Return to Meresti trainyard and talk to Vance after completing Blood Ties and getting Evan King to accept Vance's deal on behalf of the people of Arefu.
Vance owns Vampire's Edge although it's not on his person. It's in a locked (hard difficulty) sword cabinet in his room. Vance has the key to the cabinet on his person, so you can either pickpocket the key to open the cabinet, pick the lock, or kill him.
If the residents of Arefu are attacked or killed after completion of Blood Ties, Vance, along with the rest of the Family, will instantly become hostile when they see you.
Vance is the only known non-player character to have a Shishkebab equipped on his person without having picked it up somewhere.
One of his audio files is a glitch, causing him to stutter when welcoming you to Meresti.
Despite appearing rather intelligent and being able to sway quite a few followers to his cause, his Intelligence and Charisma are both only 3.
The player can overhear a conversation between Vance and Holly where Vance expresses his doubts and concerns over his ability to control and lead the Family.
After getting Ian back to Arefu, it's possible to overhear Vance and Justin still talk about Ian in the meditation area as they would before he left.
Strangely, while Vance's karma is neutral he will drop an ear when killed. It is unknown whether this is intentional or a bug.
"What does it mean? Allow me to simplify it for you since you are obviously of limited intellect. Men of science would call us cannibals, eaters of human flesh. Society labels us as monsters, demons and the unclean. I led my flock beneath the sun-baked sands of the Wasteland to keep them safe and teach them my ways."