Race
From The Vault
While people of all races survived the Great War, the term "race" in Fallout refers mostly to different kinds of human mutants, such as ghouls and super mutants, as well as pure humans themselves.
Aside from the obvious mutant-ghoul-human and cultural bigotry (tribals vs. townsfolk, Vault City vs. everyone else), racism and sexism is alive and well. A person's skin color, status, and career are always good excuses for fear and hate to build upon, although communities like NCR and Modoc would have less of a problem with this. The Great War may have brought some communities together, but it also made isolated communities as well.
[edit] Sources
The above text comes mostly from Chris Avellone's Fallout Bible 6.
