- Can be bought from the Gun Runners at its New Vegas branch.
- Can be bought from Blake at the Crimson Caravan Company.
- Can be bought from Chet at the Goodsprings General Store.
- Can be received from Muggy by giving him a Red plate or Ceramic dinner plate.
Pistol powder can be gained by breaking down any of the following at the reloading bench:
|.357 magnum round||6|
|12 gauge shotgun shell||26|
|20 gauge shotgun shell||18|
Pistol powder is part of the recipes for the following:
|.357 magnum round||8|
|.357 magnum JFP (hand load)||10|
|.44 magnum round||10|
|.44 magnum SWC (hand load)||12|
|.45 Auto +P||10|
|.45 super hand load||12|
|10mm JHP (hand load)||12|
|12 ga. buckshot||30|
|12 ga. buckshot, magnum||40|
|12 ga. coin shot||30|
|12 ga. slug||30|
|20 ga. buckshot||20|
|20 ga. buckshot, magnum||28|
|20 ga. slug||20|
|Tin grenade (Mad Bomber) (GRA)||50|