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Fallout: Brotherhood of Steel (abbreviated as FO:BoS, FOBOS or simply BOS) is an action game developed and produced by Interplay Entertainment for the Xbox and PlayStation 2 game consoles. Released on January 13, 2004, BoS was the fourth video game to be set in the Fallout universe and the first to be made for video game consoles.

The game chronicles the adventures of an initiate of the Brotherhood of Steel. Because of numerous inconsistencies with previous Fallout games, Fallout: Brotherhood of Steel is not considered part of the official Fallout canon, however some of its content could be used as "flavor" material.

When a conflict begins in the Secret Vault between Blake and scientists, a major explosion damages the Vault and its systems. CALIX partially malfunctions and is no longer capable of controlling the Vault's security robots. Soon chaos ensues, further aggravated by Super Mutants attacking the Vault.

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