Reduces poison damage by this amount.

Fallout game description

Poison Resistance is derived statistic in Fallout, Fallout 2, Fallout 3, Fallout: New Vegas and Fallout Tactics. It is also a rare resistance in Fallout 4.

This statistic reduces poison damage by a percentage as well as the chance to get poisoned. In Fallout 3 and Fallout: New Vegas, this statistic is hidden.

Fallout, Fallout 2, Fallout TacticsEdit

\text{Initial Level}=\text{Endurance}\times5

Fallout 3Edit

Poison Resistance is also present in Fallout 3. It has a much smaller part than in the previous games since only a few enemies (Radscorpions chief among them) use poison, and poison effects tend to be weak.

\text{Initial Level} \%=(\text{Endurance}-1)\times5

Example: A starting Endurance of 5.

(5-1)\times5=20\%~\text{Poison resistance}
  • The Cyborg perk can increase resistance by +10%.
  • The Survival Expert perk can add between an additional +2% to +6%.

Fallout: New VegasEdit

Fallout: New Vegas uses the same equation as Fallout 3, but Poison Resistance has much more use: there are cazadores, bark scorpions, night stalkers, and weapon poisons, all in addition to radscorpions. In Lonesome Road, there are also venomous tunnelers. Moreover, poison in Fallout: New Vegas is generally much more lethal.

Honest Hearts perks

Old World Blues perks

Items and consumables

Fallout 4Edit

Poison Resistance is not a derived statistic in Fallout 4. Its a particularly rare resistance to acquire and can only be done so via three methods:

  • Astoundingly Awesome Tales #5: Grants +5 Poison Resistance.
  • Legendary Armor pieces with the Poisoner's modifier: Grants +25 Poison Resistance. A maximum of 5 pieces can be worn at once, totalling +125 Poison Resistance
  • Med-X temporarily provides +250 Poison Resistance

Only a handful of enemies deal poison damage, such as the mirelurk queen and Bloodbugs.