Crafting plasma grenades requires considerable skill and some rare components, but the result is a compact explosive that deals a powerful combination of ballistic damage and energy damage.
Nuka Grenade: the Nuka grenade is essentially a special version of the plasma grenade, except it deals more explosive damage and its secondary damage is radiation instead of energy.
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Notes
Only the ballistic damage portion receives the benefits of damage boosting perks such as Demolition Expert and Bloody Mess, the energy damage component remains static.
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