Night stalkers are the creations of Dr. Borous at Big MT, genetic hybrids of rattlesnake and coyote DNA. They growl, howl, and whimper like regular coyotes, but hiss and rattle like snakes. Their bodies are mostly dog-like, covered in a combination of fur and scales. Their head and tail are that of a rattlesnake, including fangs and a forked tongue. A night stalker's right eye is blue with a round pupil, while the left eye is yellow with an elliptical pupil, like a rattlesnake's. They lay eggs which can be used to prepare mushroom cloud and their blood is prized as an ingredient in antivenom and hydra.
When they detect the player they strike with a leaping attack and a venomous bite or snap at the player without leaping. While the venom is not as potent as their main competition (the cazador), it can be a problem if multiple bites are received and untreated.
They can pose a particular threat in low visibility, at night (when they are active) or in caverns. Carrying Cateye, Ghost Sight, or Nuka-Cola Quartz is advisable when fighting them in low-visibility conditions. They are especially dangerous inside their dens; packs are usually large in numbers, and twisting corridors make it difficult to detect exactly where they are.
Night stalkers found in Charleston Cave and the lower level of the X-13 testing facility have the ability to cloak, making them especially dangerous. The ones in Charleston cave gained this ability from chewing on a Stealth Boy (found on a dead nightkin at the end of the cave), while the ones in the X-13 testing facility naturally have this ability. As with any other cloaked enemy, these night stalkers can only be targeted in V.A.T.S. with the Enhanced Sensors companion perk provided by ED-E. Fighting without ED-E can be done by free-aiming at the light distortion around the cloaked night stalker, similar to the appearance of a cloaked nightkin. The recommended solution, however, is to lay mines, and then get their attention. The mines will not be fooled by their cloaking. Setting them on fire works too as the fire will burn brightly and reveal their location easily. It should be noted that their invisibility will not prevent them from causing ripples in any body of water they move in, negating their ability to ambush the player.
The legendary night stalker is a very large and strong night stalker found in Bloodborne cave, west of Bitter Springs. In appearance it is visually identical to standard night stalkers and differs only in size, being about the size of a bighorner. It is normally encountered in a pack with several regular night stalkers and can kill a low level character in seconds.
It has the least amount of health out of all of the legendary creatures, but can kill a player under level 20 with about two to three bites. It is also the only legendary creature in the game that can be friendly towards the player, if the player has acquired the Animal Friend perk.
In appearance, young night stalkers are visually identical to fully grown night stalkers but are smaller in size and have weaker attacks. Although relatively weak, they are a nuisance when fought in groups of other young night stalkers and their fully grown brethren.
pcps3xbox360 Walking through the Mojave Wasteland, it is possible that the player may see a night stalker with several heads and legs. This is actually a bug in the respawn. It happens when several spawn in the same place, resulting in a number of night stalker models within each other and bound in place. Because they cannot walk they can easily be killed.
xbox360 The legendary night stalker may become stuck in the floor of the cave near the egg pile, this makes it very easy to kill as it can not attack.
ps3xbox360 Sometimes while encountering a night stalker, they will randomly die.
ps3 While engaging night stalkers via V.A.T.S. mode with the brush gun in Old World Blues all your shots may miss, even with the Guns skill at 100.
pcps3xbox360 Attempting to aim at the night stalker's head (in realtime or V.A.T.S.) often results in your shots missing. Possibly there is something off with the night stalker's collision/hit detection around its head, similar to what happens with evolved centaurs. For best results (and to avoid all of your shots missing in V.A.T.S.), target the body instead.
ps3xbox360pc If the night stalkers in Old World Blues are close enough to bite you, attempting to shoot them in V.A.T.S. mode may be completely ineffective, causing all your shots to miss.