The NCR-Raiders War is a continous fight between the New California Republic and the wasteland's various raider tribes. The NCR seeks to eradicate them as the original Khans nearly destroyed Shady Sands before it could become the NCR. When the NCR rose to power, they led great military strength against the remnants of the Great Khans, Vipers and Jackals, whom they pushed to the Mojave Wasteland.
While the war in the Core Region is over, the NCR faces difficulties in fighting the raiders in the Mojave. The Vipers and the Jackals, now being disassociated and badly equipped tribes scattered across the wasteland, attack at any given opportunity. They are not very effective or organized in their methods, making them only a minor problem. A new gang of raiders, the chem addicted Fiends start to become a bigger problem. The Great Khans however, are still the most troublesome of all raiders and are high priority targets due to the chems they supply to the Fiends.