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Mother may refer to:
- Mother Maya, an inhabitant of Megaton and a Child of Atom in Fallout 3.
- Leaf Mother Laurel, the Elder of the Treeminders in Oasis in Fallout 3.
- OasisLeafMotherLaurel.txt, dialogue for Leaf Mother Laurel in Fallout 3.
- Mother Curie III, a character in the Fallout 3 add-on Broken Steel.
- DLC03WQ03MotherCurie.txt, dialogue for Mother Curie III in the Fallout 3 add-on Broken Steel.
- Mother of the Fog, a deity worshipped by the Church of the Children of Atom in the Fallout 4 add-on Far Harbor.
- Mother, an old, wise hairy deathclaw and recruit in Fallout Tactics.
- Mother deathclaw, an overview of female deathclaws in the Fallout series.
- Mother Punga, a gigantic punga fruit growing in the Sacred Bog in the Fallout 3 add-on Point Lookout.
- Mother Darkness, a poison that can be applied to melee and unarmed weapons in Fallout: New Vegas.
- Twin Mothers, a location in Van Buren.