The Mister Handy series of robots, named so because of the robot's large number of hands, was first brought to market in 2037 as a general construction and maintenance unit by General Atomics International, with some assistance from RobCo. Primarily used in the United States and Mexico (where it was the leader in sales after the Mexico City earthquake of 2042), the Mister Handy was a reliable robot. An early bug that caused interference in the operation of the multiple arms was fixed with a hardware update in 2039, with no major problems since then. A key selling feature is the nuclear power unit (a model 238B, licensed from Calpower) and self-maintenance modes. Multiple Mister Handies are capable of keeping themselves in working condition and are also fully programmed to perform nuclear fuel replacements. Secondary programming handles radiation cleansing after refueling.
Relatively uncommon, with a few notable named versions such as Andy, Godfrey and Wadsworth. They are equipped with a buzzsaw and a flamethrower. Before the Great War, they served mainly as a household helper, and 200 years later they still have that designation.
The McClellan Mister Handy can be found in the townhome of the McClellan family in Georgetown. Before the Great War, this particular Mister Handy unit served as the personal assistant for the McClellan family, and will still perform various day-to-day chores for them, such as walking the dog and going grocery shopping if the player chooses to activate him.
Mabel Henderson's Mister Handy is one of the inhabitants of Vault 112 and part of the Tranquility Lane virtual reality simulation in 2277. It's a household maintenance robot who cooks, cleans and irons so Mabel doesn't have to. In Tranquility Lane it can be made to kill Mabel by switching the safety mode off. It will then come after you unless you destroy it or go back to the terminal and switch the safety mode on. It is the only Mister Handy in Tranquility Lane.
The following is based on Fallout 3 cut content and has not been confirmed by canon sources.
Mister Mulberry is a cut Mister Handy which was set to appear in Megaton. He is a non-hostile character, but he only has two extremely generic dialog lines. Mister Mulberry can be found in Fallout 3's game files, with his reference id being 1d770.
The McClellan Mister Handy is important and unique in that it can be controlled by a terminal in the house. Upon using the terminal, there will be five options, each allowing some form of activity with the McClellan Mister Handy:
"Deactivate Unit" - recalls the Mister Handy to its base.
"Walk Muffy"- instructs the Mister Handy to walk the McClellan's dog, Muffy. Mister Handy will travel outside, find the dog's body, and then attack you. It will refer to you as the dog when it does this, apparently as a means of reconciling its shattered reality.
"Pick up Grocery Order" - directs the Mister Handy to the nearby grocery shop. However, it will just stop at the door and come back home (if it isn't destroyed en route by super mutants or other enemies).
"Read Children Bedtime Poem" - instructs the Mister Handy to go to the children's room and begin reciting a poem. Curiously, despite its rather violent reaction to the dog being dead, it does not seem to care that the children are clearly deceased; after telling the bedtime poem, he continuously repeats "Of course, of course. Don't let me keep you," until you decide to recall him.
"Home Security Mode" - sets the unit to patrol mode, searching out any enemies.