Watkins is an initiate with the Mojave Brotherhood of Steel and she recently became eligible for journeyman status. Both of her parents died during the defense of HELIOS One and she has to choose if she wants to follow her mother, a knight, or follow in her father's footsteps and become a scribe.
When you speak directly to her, she has the voice of a young girl; when she speaks outside of direct dialogue, her voice changes to that of a woman.
Watkins has an on-going, mutual dislike of Veronica Santangelo. When the Courier is accompanied by Veronica, she will make a snide comment to Watkins about her lazy eye. Watkins will reply "I see you're still hiding your hair with that hood". On subsequent visits to Watkin's area, Veronica will angrily mutter "Watkins!", while cheerily greeting other named characters in the Bunker.
Paladin Ramos says that he was going to save Stanton and Watkins, but that she is a hell of a shot.