Mary-Joe is a bit of a nympho and not all that bright. She is the daughter of trog leader, Billy-Bob, and she is currently working for Dusty as a prostitute. However, Mary-Joe does not think of herself as a prostitute. She thinks that men are just real nice-like and give her and Dusty money as a gift. The sex part is just a fun bonus. She is very approachable as she spends most of her time in Dusty's Desires flirting with the men, and occasionally women that swing that way.
Mary-Joe has not appeared nor is she mentioned in any published game. She was to appear only in Van Buren, the canceled Fallout 3 by Black Isle Studios. It is not certain if she will appear in any future Fallout game.