A tough lady (aside from the fake illness she pretends to have), Marguerite may not share the looks of the locals, but she isn't troubled by them because she's been a Point Lookout resident since birth.
She is the descendant of a family of moonshiners. She states that the secret ingredient in her family's recipe is battery acid from fission batteries.
When first encountered, Marguerite pretends to be sick in an attempt to get the player to gather materials to cure her "Orange Fever". If your Medicine is high enough (over 70), she will drop the pretense and ask you to gather items to make moonshine.
If you have a high enough Repair skill (minimum 44), you can also volunteer to fix Marguerite's Still for 100 caps (200 caps if you pass a speech check).
After completing A Spoonful of Whiskey, Marguerite will make you her famous moonshine whenever you ask... provided you give her the ingredients.