Lump of brain
For some reason, you feel a terrible sense of loss as you look at this familiar lump of gray matter.”— In-game message
The item is in the engine room of the Duchess Gambit, on the table next to Tobar. It can only be obtained after completing the quest Walking with Spirits and asking Nadine in the Ark & Dove Cathedral to remove your scar.
- It appears that you had significantly less brain taken out than most if you observe the quantities in the other jars; this might be why you aren't affected by the lobotomy like the tribals. There is also no change to any of your stats or skills.
- Upon examining this item, the game states that "you feel a terrible sense of loss" when looking at this familiar piece of gray matter. This is a direct reference to Fallout 2's mutated toe. However, there is no option to eat your lump of brain in Fallout 3 as there was in Fallout 2 with your mutated toe.
- The 'familiar' piece of brain will be on the Duchess Gambit even before you start the quest. On the PC version, you can unlock the door with console commands and find it.
- The item was apparently meant to trigger the cut Gray Matters perk once it was picked up.