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Lizard may refer to:
- Iguana, a species of lizard appearing in the Fallout series.
- Deathclaw, a large, agile and strong species of mutant Jackson's Chameleon appearing in the Fallout series.
- Gecko, lizard-like creatures appearing in the Fallout series.
- Komodo dragon, mutated giant lizards in the American Midwest in Fallout Tactics.
- Climbing lizards, creatures found in the American Midwest in Van Buren.