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Jules may refer to:
- Jules (Fallout 2), a drug dealer in New Reno in Fallout 2.
- Jules (Fallout: New Vegas), a bodyguard for the residents and traders in North Vegas Square in Fallout: New Vegas.
- VOVNVJules.txt, dialogue for Jules in Fallout: New Vegas.
- Jules (Fallout 4), a synth met during a random encounter in Fallout 4.