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Jane may refer to:
- Jackpot Jane, Redding's creature fight manager in Fallout 2.
- Jane (Lucky 38), a securitron in the Lucky 38 in Fallout: New Vegas.
- Lucky38Jane.txt, dialogue for Jane in Fallout: New Vegas.
- Lady Jane, a caravan merchant in Freeside in Fallout: New Vegas.
- VFSDebtLadyJane.txt, dialogue for Lady Jane in Fallout: New Vegas.
- Jane (Fallout: Brotherhood of Steel), the leader of a gang of raiders in Fallout: Brotherhood of Steel.
- Real-life person: