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Jack may refer to:
- Jack, a prisoner of the Khans in Fallout
- Jack, a character from the NCR in Fallout 2
- Split Jack, a character in the Fallout 3 add-on Broken Steel
- Smiling Jack, a friendly raider merchant in Evergreen Mills in Fallout 3
- Jack Smith, a cannibal from Andale in Fallout 3
- Jack, a Boomer in Fallout: New Vegas
- Jack, a Great Khans drug dealer in Fallout: New Vegas
- Jack Maynard, only mentioned in Fallout: New Vegas
- Jack Fleming, soldier for the NCR in Van Buren
- Jack, one of Helen Galenski's kids in Van Buren
- Jack Rabbit Springs, a location in Fallout: New Vegas.
- Jack Wilson a character mentioned in a cut note in Fallout: New Vegas.
- Real-life people