Caesar's Legion, a major organization in the southwestern United States, based their culture and society on Ancient Rome, an old Italic civilization. The city of Rome and the Rubicon river are also referenced. The historic European region known as Gaul is mentioned as well, which encompassed parts of Northern Italy.
The plot of J.E. Sawyer's hypothetical Fallout: Resource Wars game would involve a crew of soldiers from the Royal Armoured Corps who become stranded in a war-torn anarchistic northern Italy and have to fight their way to the English Channel in a bunch of quickly degrading vehicles, scavenging replacements, fuel, and weapons as they go.