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The player character's Critical Hit value increases +20% faster, if the player character has 250 Radiation value. This equates to 25% of the player's maximum health being filled by radiation damage in order to activate the perk.
Behind the scenesEdit
The name of this perk 'Isodoped' is a portmanteau, combining 'isotope' and 'doped'. This is in reference to Hancock's love of chems, and isotopes possibly referring to Hancock's chemical transformation into a ghoul.