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Beginning sometime in the 2180s, a series of hostilities within the Commonwealth arose when The Institute began producing synths. Tensions and paranoia against the organization rose after the Broken Mask Incident that left 4-5 Diamond City citizens killed, the event which led to the discovery of 3rd generation synths. By 2287, many of the inhabitants of the Commonwealth began to rise up against the Institute when rumors began to rise of synths kidnapping humans only to be replace with synths who look exactly like the victim. Factions began to appear to confront the Institute's actions, however, many of the groups were at odds at one another due to their ideological differences, despite their common enemy.