|The following is based on Van Buren and has not been confirmed by canon sources.|
Dusty's Desires, located in Downtown, has plenty of booze for her customers. Her supplier is the Crimson Caravan Company. Pablo would use them, but since he used to exclusively use 3-Some, Crimson will have nothing to do with Pablo. He'll be in a funk when the player first meets him and explain his woes to a kind listener. It's up to the player if he wants to bother helping him.
The player may bring Pablo liquor and sell it to him for a good price, or the player can help 3-Some Caravan caravan with liquor runs and try to restock poor Pablo's bar. Of course ending the war would be the optimal path since that frees up a lot of things, including 3-Some's caravan routes.