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Freeside thugs will be hostile or friendly depending on your Reputation with Freeside. Either way, the Freeside thugs have little to no dialogue and interaction. The Freeside thugs respawn, regardless of your interactions with them or how they were killed.
If the player is Vilified in Freeside, a thug will approach the player and start a conversation, but realize that it's you and flee. Afterwards, thugs will be neutral and completely idle. If attacked, they (and any other thugs around them) will fight back. If spoken to before attacked, you will be notified that they are fleeing.
The Thugs appearance is completely randomized, these includes armor, weapon, hair, and even skin color.
It seems their head items (glasses, hats, etc.) are always in full condition. (xbox360confirmed)
The thugs will be hostile toward the player as long as they have a neutral or positive reputation in Freeside. However, they are usually only armed with melee weapons (though in the rare case that they manage to kill a Kings member, one may loot their body and arm themselves with a pistol), and their protection consists of basic clothing. They are easily dispatched by the player and the Kings, and will often flee during combat.
Kings will attack Freeside thugs. However, most other NPCs will panic and flee from them, and the Securitrons at the gate will usually remain neutral and will not aid the player in combat outside of the gate.
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