Fist is the leader of the super mutants occupying Trinity Tower. He is holding Rex Goodman and Strong prisoner in a cell at the top of the tower. Should the Sole Survivor enter the tower and work their way up, he will continually taunt them over the intercom. Upon reaching the top of the tower, Fist can be found outside of the cell holding Rex Goodman and Strong.
"Ha! Another human to rescue Rex. He is weak. Kill Him!"
"You only kill the weakest of us. It only makes us stronger. If they cannot kill one puny human, they are less than nothing. You fight well for a human. Now die like one. My warriors are waiting for you."
"Human, you fight almost as good as a super mutant. Maybe we will put you in a cage with Strong and Rex."