Reading a skill book permanently raises the corresponding skill by three points (four with the Comprehension perk). With a few exceptions, the skill books are identical to the books from Fallout 3. The newly added Survival skill uses the Wasteland Survival Guide as a skill book. U.S. Army: 30 Handy Flamethrower Recipes from Fallout 3 has been removed, since the Big Guns and Small Guns have been merged into the new Guns skill, which is covered by Guns and Bullets.
There are, on average, four copies of every skill book in the base game. Dead Money adds an additional copy of each skill book type, with the exception of Wasteland Survival Guide. Honest Hearts introduces the Workbench crate, a container with random loot that has a chance of containing various skill books, but no static book locations. Old World Blues adds two copies of Chinese Army: Spec Ops Training Manual and a copy of Big Book of Science, in addition to a new mechanic enabling the player to create a single copy of each book at a workbench using 25 blank books, two tubes of wonderglue and the appropriate recipe. Finally, Lonesome Road adds an additional copy of each skill book.
Types
The first number in parentheses indicates the total number of skill books with all add-ons included. The second number in parentheses is the total number of skills books with Old World Blues Skill book crafting mechanic included.
Located on the ground floor through the door next to the radioactive barrel display. There is another door behind the counter you must pick (HARD difficulty), the book is located on a shelf past the door.
In the Goodsprings Home inhabited by Trudy and Sunny Smiles, East from the Schoolhouse, on a bookshelf. (Must be stolen unless the Run Goodsprings Run quest has been completed).
On some papers, by the corner desk inside the Sharecropper Barracks near the four water towers in the northeast corner of the fenced in area. (Must be stolen)
In the eastern most room of the switching station there is a huge machine on the south side of the room. The book is located on the catwalk that runs around the machine. Its the only portion of catwalk in this room that you have to jump to.
On a bookshelf facing the wall (hidden from view) on the S/E landing up one flight of stairs from the ground floor interior entrance. Can be exposed by placing/throwing explosives onto the bookshelf, underneath the filing cabinet.
Upstairs in the main building, lying on a bed in the same room with the east terminal password. (Head to the right from main entrance, through the pool room, and right up the stairs.)
On the metal sill, opposite the reloading bench, in the area with the office. Though the location exists without the add-on, it is sealed by a keyless lock. Note: If the game is unpatched (installed straight from disk without being patched), the door will be unlocked and you will be able to enter and get the book.
Puesta del Sol Switching Station in the south center of the map on the upper level next to the terminal that shuts off power to the protected speakers. It is very difficult, but possible, to reach without Christine (her perk delays the speakers) and disarm the trip wire before your collar detonates.
It is stuck underneath the bed in the same room where you first meet Dean Domino. The book is only obtainable by using explosives and dropping throwing spears to force the book out.
It is inside the worker barracks on the back left shelf under a first aid box. (Must be stolen). An owned copy of Dean's Electronics can be found here as well.
Go to the second floor and jump on to the support beams. From there, jump down into the cashier's caged area. The book is on the floor behind the cashier's desk.
1st Floor, past the 100 Lock/Security door on top of the safe. (Or sneak up to the 3rd floor and get the key from the suitcase next to the skeleton). The room can also be accessed through a hole in the floor of a room on the west side of the 2nd floor (Must pick the lock on the door. It is a level 75 lock <Hard>).
Right before you enter the vault door turn around and jump down to the pipes below the walkway, there is a duffle bag with the book inside. The only way back is to go east from the bag and jump on the valved pipe then back to main platform.
With the total amount of skill points earned from reading every obtainable skill book (not counting the ones found as random loot in Honest Hearts), and with the Comprehension perk, the PC will have gained a total of 384 skill points (288 without it). The Workbench crate skill books found in Honest Hearts can make up an additional 64 skill points with Comprehension (48 without), assuming the maximum of 4 skill books per crate.
Although it is possible to obtain the maximum of 16 (non combat related) skill books the likelihood is extremely low (see Workbench crate page). It would be more realistic to hope for the total amount of 8 skill books. Theoretically approximately 1 out of 5 save/reload trials (before entering the caves) or using the console, selecting it, and typing resetinventory should result in 2 random skill books. If the player has the Comprehension perk it still should be enough to max out all skills.