Disease Resistance is a derived statistic in the SPECIAL character system.
Overview[]
Each uncooked consumable, attack from a diseased creature, or environmental hazard has a percentage-based chance of inflicting a disease. Disease Resistance decreases the chance for a player to contract a disease from all sources, but certain perks may reduce the odds for a specific source.
Disease Resistance can be increased by being Fed and Hydrated, which require maintaining a player's food and water needs. Each effect increases disease resistance by 15-35%. The perks Iron Stomach and Thirst Quencher will also increase disease resistance when eating and drinking uncooked or spoiled food. The Vaccinated perk increases resistance to disease specifically from attacking creatures. The Natural Resistance perk increases resistance to diseases contracted from the environment.
The Antiseptic legendary effect grants 25% environmental disease resistance per piece, up to a maximum of 125%. Disease resistance can also be acquired from consumables.
Subcategories[]
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- Combat
- Diseased enemies
- Food
- Moldy food
- Raw food
- Spoiled food
- Drink
- Dirty water
- Drinking from water sources
- Fermenting alcohols
- Toxic water
- Environment
- Beds
- Traps
- Water
- Inhalation
Buffs[]
There are multiple ways to increase Disease Resistance:
| Food/Drink (only 1 at a time) | ||
|---|---|---|
| Item | Perk/Mutation | Buff |
| Grape perk bubblegum | +5%  2 minutes
| |
| Inert flux | +5% 30 minutes
| |
| Simple bloodleaf tea | +5% 30 minutes
| |
| Chicken noodle soup | +10% 30 minutes
| |
| Mountain hocks | +10% 30 minutes
| |
| Razorgrain soup | +10% 30 minutes
| |
| Company tea | +20% 60 minutes
| |
| Infused bloodleaf tea | +20% 60 minutes
| |
| Vegetable medley soup | +20% 60 minutes
| |
| Aid | ||
|---|---|---|
| Item | Buff | |
| Antibiotics | +50% 90 minutes
| |
| Survival Needs | ||
|---|---|---|
| Value | Perk/Mutation | Buff |
| Fully Fed / Well Fed | Standard | +35% |
| Rejuvenated 1 | +40% | |
| Rejuvenated 2 | +45% | |
| Fed / Partially Fed | Standard | +15% |
Debuffs[]
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Formula[]
Disease Resistance is affected by the player's current Endurance stat (END). This includes the base SPECIAL as well as any END buffs or debuffs. Disease Resistance stops scaling at Endurance 15.
| Endurance scaling | |
|---|---|
| Endurance Value | Disease Chance Multiplier |
| 1 | 2.0 |
| 2 | 1.9 |
| 3 | 1.8 |
| 4 | 1.7 |
| 5 | 1.6 |
| 6 | 1.5 |
| 7 | 1.4 |
| 8 | 1.3 |
| 9 | 1.2 |
| 10 | 1.1 |
| 11 | 1.05 |
| 12 | 1.0 |
| 13 | 0.95 |
| 14 | 0.9 |
| 15 | 0.85 |
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