If the Lone Wanderer has a Science skill of 75 or more, they can deactivate both Deputy Steel and Deputy Weld using the computer terminal in the armory to avoid wasting ammunition or getting hurt. If a Stealth Boy is used before entering, the Lone Wander might sneak over to the terminal undetected to deactivate Deputy Steel then loot the place without any conflict.
If Deputy Weld, Megaton's protectron guard, is destroyed after Broken Steel is installed, Deputy Steel will assume Deputy Weld's post. In the Game of the Year edition this is not the case: if Deputy Weld is destroyed, Deputy Steel will remain in the armory. However, Deputy Steel will still show up if the Lone Wanderer attacks Deputy Weld, as will Lucas Simms.
If the Lone Wanderer enters the armory in Megaton, then he will become hostile.
Sometimes, when you attack him he says "What is your major malfunction, maggot?", which is a reference to the 1987 movie Full Metal Jacket. Gunnery Sergeant Hartman says this right before he is shot by Pvt. Lawrence ("Pyle").