This quest can be started randomly when speaking to Preston Garvey or listening to Radio Freedom, who tells you that a settlement needs help defending its artillery piece. On arrival one of the settlers will tell you the Brotherhood of Steel has been snooping around, and they believe they mean to destroy the artillery.
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- This is essentially the same as Defend the Settlement but with the Brotherhood of Steel as antagonists and a specific objective to defend the artillery piece rather than the Settlement as a whole. This will not stop the Brotherhood soldiers from firing on the settlers however.
- It seems you get this quest for siding against the Brotherhood, regardless of which faction you choose to do so with.
- Failing to provide assistance can result in a loss of settlers and/or damaged defense equipment.