Popular with beatniks and intellectuals before the Great War, Daddy-O raises Intelligence and Perception, but lowers Charisma, for a limited period of time.”— Loading screen hint
Daddy-O is a small syringe with two vials filled with a bright orange liquid inside. According to terminal entries in-game, the drug is popular with beatniks and intellectuals of the time.
- Fort Hagen, in a first aid kit on the upper level. (possibly randomly spawned)
- South Boston police department, in a toilet bowl on the ground level.
- Vault 95, on the right hand side shelf of a med-filled closet in the lower levels of the vault.
- Vault-Tec Workshop Vault 88, in the room above the North-East sector Vault-Tec control board, in a first-aid kit on a barrel. (possibly randomly spawned)
- Southeast off of the coast at Kingsport Lighthouse on one of the bigger shipwrecked structures (the one with the red buoy), in a first aid kit in the western shack.
- Far Harbor (add-on) In Far Harbor, at a small dock located just east of the Harbor Grand Hotel on a picnic table.
- Diamond City, sold at Solomon's Chem-I-Care, Fallon's Basement, and Myrna's Diamond City Surplus (trading, rare).
- Drumlin Diner, sold by Wolfgang (trading, rare).
- Goodneighbor, sold by Fred Allen in Hotel Rexford (trading, rare).
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