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Curtis may refer to:
- Curtis (Fallout), a farmer in Shady Sands in Fallout.
- Curtis, a child in Vault City in Fallout 2.
- Kurtis Rega, one of the original residents of Vault 87, who died during the FEV experiments, mentioned in Fallout 3.
- Ronald Curtis, a Legion spy posing as an NCR officer in Camp McCarran in Fallout: New Vegas.
- Curtis Debord, a soldier who fought, and died, during the First Battle of Hoover Dam, mentioned in Fallout: New Vegas.