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The following is based on Fallout Tactics and some details might contradict canon.
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People of Springfield. You've all known me as Mayor Avellone for two years now and as Chris Avellone for many years before that. I've always been proud serving this town and all its people - and that's a fact.
Avellone reached the mayor's seat after the previous mayor disappeared under suspicious circumstances. However, Avellone took to his new power and started causing trouble. This lead to an assassination plot developing that was only averted due to the protection of a squad from the Brotherhood of Steel. He was made to sign a 'Bill of Monster's Rights'; this political stance angered some of Springfield's far-right, as well as human activists who refused to acknowledge the "sub-humans" as near equals.
In 2197, the Brotherhood of Steel sent a squad to Springfield to protect Avellone from a plot to assassinate him. After the BOS squad rescued the mayor, he became quite the puppet official and the extra resources helped fuel the Brotherhood machine. He signed the "Bill of Monster Rights", which gave some limited rights to ghouls (such as a ghouls being entitled to a payment equal to, or greater than, half that of a pure bred human).
"We shouldn't hate the ghouls for being what they are. They can't help it if they were mutated into hideous looking monsters. Remember, that inside that monster, under the rotting flesh, the flaking skin, and the misshapen features is a second-class citizen."
"I know you may not want to pat a ghoul on the back and that's OK. Just don't burn its house down.."