Caravan trade route is a paper note in Fallout 3. It can be obtained from Uncle Roe in Canterbury Commons when starting the unmarked quest Merchant Empire.
The Xs mark the following map locations starting from Canterbury Commons (Further NE X) then counter clockwise:
Temple of the Union (up NW), Agatha's house (down SW), Paradise Falls (up NW), Arefu (down S-SW), Evergreen Mills (down SW), Megaton (straight East), Rivet City (down SE).
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