Calmex is a consumable item in Fallout 4.


Calmex is believed by many to be a pre-War light tranquilizer for veterinarian purposes. Despite these rumors that this medicine is for animals, the value of it is exceptional due to its pre-War quality.

This tranquilizer doesn't work as a painkiller when administered to humans. However, it still carries a high enough dosage to cause a kind of head high that boosts some survival senses that are ordinarily dulled by reasoning. [citation needed]


A rare consumable that boosts the user's stealth capabilities, increasing the sneak attack multiplier and raising the user Perception and Agility stats by 3.



This item cannot be found in any fixed locations. It is an extremely rare loot drop or item sold by chem dealers and general dealers:


  • Calmex shares the item model with Med-X.

Behind the scenesEdit

50 Vault-Tec C.E.O.The following is based on unverified behind the scenes information and has not been confirmed by canon sources.

Due to the similar name and function, Calmex appears to be based on the real-world drug "Calminex" which is a brand of tranquilizer used for veterinary purposes.

See alsoEdit