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For the Buffout that appears in the Fallout series, see Buffout.

Buffout is a powerful steroid that gained popularity with athletes before the Great War. It grants temporary bonuses to Strength, Endurance and maximum Health.

— Loading screen hint

Buffout is a consumable item in Fallout 4.


The addiction effects are -1 STR and -1 END once Buffout has worn off. It appears as a small brown jar with a white lid, presumably holding pills of Buffout inside of it.



  • At the E3 showcase, it is in the Sole Survivor's inventory when they obtained their Pip-Boy.[1]
  • It is the only major chem that cannot be made at a chemistry station.



  1. Fallout 4 - E3 Showcase World Premiere

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