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| ||For the Buffout that appears in the Fallout series, see Buffout.|
Buffout is a powerful steroid that gained popularity with athletes before the Great War. It grants temporary bonuses to Strength, Endurance and maximum Health.”— Loading screen hint
The addiction effects are -1 STR and -1 END once Buffout has worn off. It appears as a small brown jar with a white lid, presumably holding pills of Buffout inside of it.
- In Diamond City, next to the chem dealer.
- At the E3 showcase, it is in the Sole Survivor's inventory when they obtained their Pip-Boy.
- It is the only major chem that cannot be made at a Chemistry station.
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