Boxing is a sport that makes an appearance in Fallout and Fallout 2. In Fallout, the player can take bets in Junktown, for the champion Saul. In Fallout 2, entering the Jungle Gym of New Reno, you get to box against 4 characters; Joqq, Pete McKneely, Evan Holyfeld, and The Masticator. After defeating these characters, you gain the Prizefighter perk and some fame.
The Masticator can bite your ear off which you will find in your inventory afterwards as a unique item named player's ear. This event, however, reduces your charisma by 1 point. See The Masticator "Odd Habits" for more information.
Boxing is hosted by Stuart Little and he will ask you for 50% of your pay from boxing. Upon entering the ring, you are given your own boxing gloves, but under the Shark Club, you can find some plated boxing gloves, allowing for some cheating to begin.