Operation: Anchorage (add-on)One can talk with Defender Morrill at the beginning of Operation: Anchorage, so the Lone Wanderer can come through after the elevator, though this is only for the flavor effect, as they will let you in without the perk anyway.
fo3oaOne can use this perk on Defender Sibley in the beginning of the Operation: Anchorage quest-line, where he will lead the player character to Protecter McGraw without the aggression. He still turns on the player character at the end, though.
The Pitt (add-on)One can convince Ramsey into selling slaves to the player character during the quest Into The Pitt.
Dead Money During Strike Up the Band, after helping Dean Domino with the Sierra Madre holograms, one can immediately persuade him into doing his job with the fireworks display by claiming "a man with cold feet isn't somebody I'd share a bed with."
Black Widow derives its name from the habit of female Latrodectus (black widow spiders) to cannibalize their mates during or after mating. It is also the official FBI designation for a woman who murders her husband(s), usually in a serial fashion and/or for monetary gain.