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Betty may refer to:
- Betty - The identity of Dr. Stanislaus Braun in Fallout 3's Tranquility Lane.
- Bumble - A child at Little Lamplight in Fallout 3 whose real name is "Betty" .
- Betty - A premade playable character in Fallout Tactics.
- Betty - A ghoul trader in Van Buren.
- Big Betty - A super mutant player character in Fallout Extreme.