Fallout: New Vegas locations project
Along with its neighbor Hopeville, Ashton was home to several United States Armed Forces nuclear missile bases and silos. In 2077, along with the rest of the world, it was hit by a nuclear arsenal while it launched off its own.
Centuries later, it was part of a large community when the Courier opened supply lines to the town. However, he/she had accidentally detonated a nuclear weapon at Ashton and Hopeville, and the entire city fell silent. Ashton became part of what was known to be "The Divide".
Ashton is now a wreck of the skeletons of buildings and camps of Marked Men who've survived the brutality of the Divide.