Anne was the team leader of a scouting party that left the Vault to explore the outside world sometime during February 2241. After completing the survey, Anne records her team's findings in a report to the Vault overseer, The Unnamed Vault 101 overseer.
In the G.E.C.K. description for one of Lucy Palmer's dialogue files, she is listed as having been killed in the wasteland long ago. She is implied to be the former owner of the Armored Vault 101 jumpsuit in Moira's possession.
Anne is mentioned in a scouting report in Overseer Alphonse Almodovar's computer.