Under constant supervision from Stanley Armstrong, Andy is a Mister Handy robot, although a more apt title would be "Mister Liability." Due to a lack of specific motor parts, Andy is prone to articulated blade spasms, which have already claimed a cake.
Andy works in Vault 101, apparently for the maintenance department under Stanley Armstrong. At the Lone Wanderer's 10th birthday party, Andy attempts to cut the birthday cake, with disastrous results.
After James' escape from the Vault, Andy is assigned to be the vault's new medic. In his one surgical operation, Andy decides to treat Beatrice's sprained big toe by amputating the whole leg. He amputates the wrong leg, and Beatrice dies as a result. Andy is reassigned as a cleaner, rather ironically the first job being cleaning up the mess he made of Beatrice.