Andrea began her career in the Brotherhood of Steel as a scout/explorer. She was originally sent east to confirm the existence of the Maxson Bunker and to use it as a staging area for her explorations. She was accompanied by a team of four Paladins.
After the war broke out between the BOS and the NCR, Andrea was promoted to commander and placed in charge of the bunker. She also received the title of Elder Paladin, as did her four companions.
Andrea is not comfortable with leadership and would prefer to spend her time exploring. She is not very organized and is content to let people do what they are best at with little supervision. Fortunately, her supporting staff recognize her flaws and cover for her.
Andrea's most ardent supporter is her best friend and fellow paladin, Glenn Deering.
Andrea Brixley has not appeared nor is she mentioned in any published game. She was to appear in Van Buren, the canceled Fallout 3 by Black Isle Studios. It is not certain if she will appear in any future Fallout game.