Prior to the Great War, Adams Air Force Base had been the headquarters of Strategic Air Command, though that position was later relegated to Offutt Air Force Base in the Midwest. The base had not been fortified prior to the arrival of Enclave troops, and most of the robotic defenses had been offline.
This area is viewed by heading straight ahead at the entrance to the base. Both gates are inaccessible. Glitching in or using console commands to enter reveals nothing noteworthy, and the houses cannot be accessed because they have no doors.
There is a mini nuke located in a nook above an awning that is reachable from the roof via a walkway covered in steel colored pipes. During the quest Who Dares Wins, this roof will overlook a large number of Vertibirds. When coming from the Presidential Metro, keep moving right, and up some stairs. They are on a green tin awning at the far side of this roof. From the metal housing (with the computer and first aid boxes), look to the right, towards the Vertibirds (some may have first aid boxes).
There is a mini nuke on the double-stacked large crates in Hangar 2B (the one with the covered catwalk patrolled by the sentry bot). Hop onto the roof while walking up the south end of the covered catwalk, enter through the northwest hole in the roof and make a running jump (while standing) from the top of the cage to the stacked crates.
2x mini nukes in a corridor of the aircraft hangar with three derelict jet planes inside (along the western edge of the map, near the center). One is hidden under a desk in the southeast corner; the other is hidden behind a filing cabinet.
Enclave soldier log #1- located on a small platform behind a large machine, in the alley directly west of the rooftop where the Sector 2 artillery note is located. When in the alley and looking northward, turn left (west) and enter the opening between the walls. Following the alley, then climbing the stairs, there is a large machine. A dead Enclave soldier is behind the machine, with the holotape on his body.
There are numerous deathclaw cages, but only some of the deathclaws inside have Enclave transmitters on their heads, meaning they will be hostile to both the player and the Enclave if released. When using the Deathclaw control scrambler, it may be a good idea to see if a deathclaw has a transmitter before releasing it.
After the Who Dares Wins quest, the Brotherhood of Steel will occupy the base with 7-20 soldiers, making it the largest BoS base in the game besides the Citadel and Project Purity.
If the Galaxy News Radio quest is not complete, there is a brief window where the GNR signal can be picked up.
ED-E, a companion in Fallout: New Vegas was created at this base by an Enclave scientist named Whitley.
pcxbox360 Sometimes wrecked Vertibird pieces hang in mid-air then drop out of the sky when approached. [verified]
pcxbox360 Sometimes after saving and exiting outside of the mobile base crawler, upon reloading, The Enclave and BoS soldiers previously killed will come back to life wearing nothing. Killing and searching these soldiers will get you more armor and weapons. [verified]
xbox360 The deathclaw cages can be lock-picked (hard), then relocked using the attached deathclaw pen door terminal (needs to be hacked) multiple times, giving a lot of XP. (NOTE: Breaking the lock will also disable the terminal option to open the door) [verified]