The abandoned home is a location found in Grayditch. There are two buildings named "abandoned home". The first is adjacent to Brandice's house, the door of the second is clearly visible from Marigold station.
Both homes contain an entry area which opens onto the main living room, with a bathroom and kitchen/dining area making up the lower floor. Upstairs, there is a bedroom containing various items.
These abandoned homes appear only in Fallout 3.