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APC may refer to:
- Armored personnel carrier, a drivable vehicle designed by the Midwestern Brotherhood of Steel in Fallout Tactics.
- Unnamed armored vehicle, an IFV of the United States Armed Forces before the war. Rusted and decaying IFVs can be found scattered around the Greater Boston area, usually at military checkpoints. This vehicle appears only in Fallout 4. Incorrectly labeled as an 'APC' in game's code.